Department of Chemistry · Westfield University

Yanan Lab for
Nanomaterials
& Self-Assembly

We engineer programmable nanostructures with precisely controlled optical, chemical, and biological properties — advancing diagnostics, drug delivery, and functional materials.

12+
Publications (2021–2024)
$6M+
Research Funding
10
Lab Members
4
Research Areas

Research Areas

Four interconnected directions in nanoscience

Programmable Nanostructures

We engineer metal nanoparticles — gold, silver, and platinum — with atomically precise shapes and surface chemistries. By controlling the s…

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Nanomedicine & Drug Delivery

We design nanocarriers that exploit the enhanced permeability and retention (EPR) effect to passively accumulate in solid tumors, then rele…

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Plasmonic Biosensors

Plasmonic nanostructures transduce molecular binding events into optical signals with extraordinary sensitivity — down to single molecules…

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Functional Self-Assembly

Beyond individual particles, we harness the power of self-assembly to build higher-order superstructures — colloidal crystals, liquid cryst…

Yanan Lab researchers at work

Our Lab

Curiosity-driven science at the nanoscale

Featured Publications

Selected recent work from the lab

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★ Featured

Sara Kim , Luca Ferrari , and Yanan Huang

DNA-Directed Three-Dimensional Assembly of Gold Nanorods into Chiral Superstructures with Programmable Optical Activity

Nature Materials, 2024

self-assemblynanostructuresDNA nanotechnology
★ Featured

Priya Patel , James Okafor , and Yanan Huang

pH-Responsive Polymer-Gated Mesoporous Silica Nanoparticles for Tumor-Selective Doxorubicin Release

ACS Nano, 2024

nanomedicinedrug-delivery
★ Featured

Luca Ferrari , James Okafor , Ethan Brooks , and Yanan Huang

Femtomolar SERS Detection of Circulating Tumor DNA Using Gap-Enhanced Gold Nanostar Dimers

Journal of the American Chemical Society, 2024

biosensingnanostructuresSERS

Latest News

Updates from the Yanan Lab

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Yanan Lab Receives $1.8M NSF Grant for Next-Generation Plasmonic Biosensors
award

Yanan Lab Receives $1.8M NSF Grant for Next-Generation Plasmonic Biosensors

The National Science Foundation has awarded the Yanan Lab a four-year, $1.8 million grant to develop SERS-based biosensors for early-stage cancer detection.

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Nature Materials Paper on DNA-Directed Nanorod Assembly Published
publication

Nature Materials Paper on DNA-Directed Nanorod Assembly Published

Our paper on using DNA scaffolds to assemble gold nanorods into chiral superstructures with programmable optical activity has been published in Nature Materials.

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announcement

Dr. Sara Kim Joins the Lab as Postdoctoral Researcher

We warmly welcome Dr. Sara Kim, who joins us from Stanford University where she completed her PhD on DNA-mediated nanoparticle self-assembly.

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Join the Yanan Lab

We welcome motivated PhD students, postdoctoral researchers, and undergraduates passionate about nanoscience.

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